For Severe Depression and Chronic Pain Syndromes

Severe depression and chronic pain syndromes can be challenging conditions to manage. When commonly used medication and therapy fails to work, the patient is left wondering where to turn for help. The good news is Ketamine Infusion Therapy has been found to offer relief for many who have no other options.

If you are suffering from depression or pain that is not responding to treatment please contact us today.

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About Ketamine Infusion Therapy

Patients with major depressive disorders, bi-polar depression, PTSD, and severe anxiety states sometimes suffer with sever depression that does not respond to oral antidepressants or other therapy. The good news is that Ketamine infusion therapy has emerged as an effective treatment option for many patients suffering from treatment resistant depression.

Ketamine is given as a low dose infusion and works differently from other currently available medication by blocking a neurotransmitter in the brain called glutamate. Research goes on to fully understand the effects of blocking the glutamate (NMDA) receptor, but it appears that neuron connection damage caused by “being depressed” is reversed allowing for healthy connections to develop. The result is a dramatic and rapid improvement in severe depression.

Patients with mild depression, situational depression, or mood swings are not candidates for Ketamine infusion therapy.

Chronic pain is a debilitating condition and can be very difficult to manage. Patients with severe pain conditions such as reflex sympathetic dystrophy (RSD), complex regional pain syndrome (CRPS), and other neuropathic conditions such as Fibromyalgia, post herpetic (shingles) neuralgia, and post-treatment Lyme disease neuropathy that are not controlled with prescription pain medication, injections or other therapy may respond to Ketamine infusion therapy.

Ketamine is known to block the glutamate (NMDA) receptor in the spinal cord, which is an important pathway for the transmission of the pain signal to the brain in chronic pain patients. Blocking this excessive pain signal allows the brain to reset and stop interpreting sensations as painful.

Ketamine infusion is an out patient procedure done in a private setting. Patients sit in a recliner while receiving the infusion and are monitored continuously with an anesthesiologist immediately available throughout the procedure. Infusions for depression treatment last 2 hours. Chronic pain conditions require longer infusions. You may listen to relaxing music or just experience the infusion. 

It may take several Ketamine infusion treatments for symptom relief to occur.

You will not lose consciousness. You may feel like you are floating or disconnected and have some light and sound sensitivity. Most patients tolerate the infusions quite well. Expect to be light headed or dizzy for about an hour after the infusion. You must arrange for someone to bring you and take you home. They may remain with you during the infusion if you wish.

It will take several hours for symptom relief to occur. At some point you will begin to notice an improvement in your functionality but mood improvement may take some time. Your mental healthcare provider will determine if more treatments are necessary.

Why Choose Omaha Pain

Experienced Pain Doctor


As a dedicated team of medical professionals, we at Omaha Pain Physicians work tirelessly to restore our patients’ quality of life and promote greater overall health. Combining cutting-edge medicine with our uniquely natural approach, we are a practice that treats the whole patient - from physical state to emotional well being.


Customer Service

From the moment your are greeted upon entering the clinic, you will have an unparalleled experience of excellent care. Omaha Pain Physicians work hard to ensure quality patient care in a kind, timely, and effective manner.

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Cutting Edge Treatments

At Omaha Pain Phyisicians, we are using the latest therapies developed to treat pain, promote overall wellness, and improve your quality of life.

Frequently Asked Questions

Recent research has shown that intravenous infusion of low dose ketamine can be very effective in treating severe depression and certain chronic pain conditions that are resistant to all other therapy. Ketamine, discovered in 1962, has been used extensively in patient care that requires analgesia and anesthesia.

Yes, Ketamine infusion therapy for depression and pain control is an outpatient procedure requiring no hospital admission..

We do not require a formal written referral from your doctor or therapist, but we do require evidence from your medical history for your treatment resistant condition. We reserve the right to contact you doctor or therapist to confirm your medical history and treatment if necessary.


Every patient is different; however, many studies have reported a 70% success rate for the patients that receive ketamine infusion therapy. This is very encouraging, and we will assess the effectives of the treatment after you have received two infusions.


The cost of the infusion series will depend on the amount of infusions required and varies from patient to patient.  This will be discussed at your appointment.

We do not accept any insurance plans or Medicare, but will provide you with health insurance claim forms for you to submit for reimbursement.

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